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Indiana State Department of Health

Genomics Program Home > Heelstick Heelstick

What is a heelstick?

Before every baby goes home from the nursery, he or she has a small amount of blood taken from his or her heel. This is called a heelstick. The blood from the heelstick is used to test for a specific group of conditions. If anything concerning is found, the Newborn Screening Laboratory contacts the baby’s doctor.

What conditions are included in Indiana's heelstick?

Below is a complete list of conditions included in Indiana's heelstick.  Links have been provided for some of the conditions below, for information on conditions without links please ask your health care providor.

For a list of resources for families of children with newborn screening conditions, please click here.

Endocrine Disorders

    1.     Congenital adrenal hyperplasia (CAH)
    2.     Hypothyroidism

Hemoglobinopathies

3.    Sickle cell anemia (includes testing for S/C anemia & beta-thalassemia)

Metabolic conditions

Amino Acid (AA) Disorders (includes urea cycle disorders) (en espanõl)
4. Arginase deficiency (argininemia)
5. Argininosuccinic aciduria
6. Biopterin cofactor defects
7. Citrullinemia (CIT type I)
8. Citrin deficiency (CIT type II)
9. Homocystinuria (HCY) (en español)
10. Hypermethioninenemia
11. Hyperphenylalaninemia
12. Maple syrup urine disease (MSUD) (en español)
13. Phenylketonuria (PKU) (en español)
14. Tyrosinemia type I
15. Tyrosinemia type II
16. Tyrosinemia type III

Fatty Acid Oxidation (FAO) Disorders (en espanol)

    17.  2,4-dienoyl-CoA reductase deficiency
    18.  Carnitine-acylcarnitine translocase deficiency (CACT)
    19.  Carnitine palmitoyltransferase deficiency I (CPT IA)
    20.  Carnitine palmitoyltransferase deficiency II (CPT II)
    21.  Carnitine uptake defect (CUD) 
    22.  Glutaric acidemia type II (also called GA type II, electron transfer flavoprotein deficiency, ETF deficiency, multiple acyl-CoA dehydrogenase deficiency, or multiple FAD dehydrogenase deficiency)
    23.  Long chain hydroxyacyl-CoA dehydrogenase deficiency (LCHAD)
    24.  Medium chain acyl-CoA dehydrogenase deficiency (MCAD) (en español)
    25.  Short chain acyl-CoA dehydrogenase deficiency (SCAD)
    26.  Short chain hydroxyacyl-CoA dehydrogenase deficiency (SCHAD)
    27.  Trifunctional enzyme deficiency
    28.  Very long chain acyl-CoA dehydrogenase deficiency (VLCAD)

Organic Acidemias (OA) (en español)

    29.  2-Methylbutyrylglycinuria (2-MBG) 
    30.  3-Hydroxy-3-methyl glutaric aciduria (HMG) 
    31.  3-Methylcrotonyl-CoA carboxylase deficiency (3-MCC deficiency) (en español)
    32.  3-Methylglutaconic acidemia (3-MGA)
    33.  Beta-ketothiolase deficiency  
    34.  Glutaric acidemia, type I (GA type I)
    35.  Isobutrylglycinuria (IBG) 
    36.  Isovaleric acidemia (IVA) 
    37.  Malonic aciduria (MAL)
    38.  Methylmalonic acidemia (MUT or methylmalonyl-CoA mutase)
    39.  Methylmalonic acidemia with cobalamin disorders (CblA & CblB)
    40.  Methylmalonic academia with homocystinuria (CblC & CblD)
    41.  Multiple-CoA carboxylase deficiency
    42.  Propionic acidemia

Other

    43.  Biotinidase deficiency (en español)
    44.  Cystic fibrosis
    45.  Galactosemia (classic galactosemia or G/G) (en español)
Includes testing for galactosemia D/G variant & other galactosemia variants (en español)

Click here to read the HIPAA Notice of Privacy Practice for the ISDH Newborn Screening Program.

Click here to read the HIPAA Notice of Privacy Practice (en espanõl)

Other Resources

Indiana's Newborn Screening Brochure (en español)

After Newborn Screening Brochure (en español)