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Indiana State Department of Health

Indiana State Department of Health

ISDH Home > Public Health Protection & Laboratory Services > Epidemiology Resource Center (ERC) > Surveillance and Investigation > Infectious Disease Epidemiology > Newsletters > Indiana Epidemiology Archived Newsletters > Epi_Newsletter_June_2008-Page2 Indiana Tuberculosis Annual Summary 2007

Cases= 129

Crude Incidence Rate per 100,000 population = 2.0 (U.S. 2006 = 4.6)

Race and Ethnicity-specific Incidence Rates per 100,000 population [1]
White = 1.5
Black or African-American = 5.0

Asian = 18.1

Hawaiian Native or other Pacific Islander = N/A

American Indian or Alaska Native = N/A

Hispanic or Latino, all races = 11.3

Gender-specific Incidence Rates per 100,000 population

Male = 2.6

Female = 1.5

Executive Summary

During 2007, 129 new cases of tuberculosis (TB) were reported to the Indiana State Department of Health.  Figures 1a and 1b show long-term and 6-year trends, respectively.  TB cases were reported by 33 of Indiana’s 92 counties.  The three most populous counties (according to the estimated 2006 census), Marion, Lake, and Allen, accounted for 56 percent of all new TB cases.  While the number of reported cases in Marion County decreased from 47 cases in 2006 to 42 cases in 2007, the number of reported cases in both Lake and Allen Counties increased during 2007.  Allen County increased from 10 cases in 2006 to 15 cases in 2007; Lake County increased from 10 cases in 2006 to 16 in 2007.  The number of reported cases in Kosciusko County has continued to decline since the 2005 outbreak.  The number of reported cases in the Northwest region (Figure 2) increased from 12 in 2006 to 22 cases in 2007.  The number of reported cases in the Southern region experienced a similar increase, with 11 reported cases in 2006 and 22 in 2007.  Sixteen new Indiana genotype clusters (two or more molecular matched isolates) were identified in 2007.  Seven of these clusters were located exclusively in Marion County.

High-risk populations include: children, persons infected with HIV, and persons who abuse drugs and/or alcohol.  Reporting for HIV increased in all age groups:  In 2007, HIV status was known for 87 percent of those in the 25-44 age group, compared to 66 percent in 2006 (Table 1).  Pediatric cases decreased in 2007 to 6 percent from 13 percent of the total reported cases in 2006 (Figure 3).  Excess alcohol use and non-injection drug use increased from 18 percent in 2006 to 26 percent in 2007 and 4 to 9 percent, respectively (Table 2).  The percentage of cases started on appropriate therapy increased from 82 percent in 2006 to 88 percent in 2007 (Figure 4).  There was one multi-drug resistant case in 2007 and eight cases resistant to Isoniazid only (Figure 5).

U.S.-born cases continue to make up the majority of TB cases diagnosed in Indiana (Figure 6).  Of those non-U.S.-born cases, the majority come from Central/South America (Figure 7).  National trends show most non-U.S.-born cases are diagnosed within the first three years after entry into the U.S.  In Indiana, the largest number of non-U.S.-born individuals diagnosed with TB have lived in the U.S. for longer than five years.


Figure 1a.                                                                               

Figure 1b.

Table 1.
Figure 2.

Figure 3.

Table 2.

Figure 4.

Figure 5.


Figure 6.

Figure 7.

For the full report, go to:


[1] Incidence rates based on population estimates 2006 census

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