Avian Influenza (Flu)
Avian influenza (AI) viruses (sometimes referred to as bird flu) infect wild birds, poultry, and other mammals. AI viruses are divided into two groups based on the severity of the disease they produce in poultry: low pathogenicity avian influenza (LPAI) or highly pathogenic avian influenza (HPAI). While LPAI viruses typically cause milder illness and may circulate undetected, HPAI viruses are highly contagious and cause high mortality in poultry. While human illness to AI viruses are rare, both LPAI and HPAI viruses can cause human illness ranging from mild to severe.
What's Happening Now
HIGHLIGHTS: Current U.S. Bird Flu Situation in Humans
- Sporadic infections with highly pathogenic avian influenza A(H5N1) viruses in mammals have been reported in the United States, Canada, and other countries, but the risk to the general public remains low from these viruses.
- Influenza A(H5) is widespread in wild birds worldwide and is causing outbreaks in the U.S. poultry and dairy cattle with several recent human cases in U.S. dairy cattle workers.
- Only four human infections with low pathogenic avian influenza A(H7N2) viruses have ever been identified in the United States.
- No known human-to-human spread has occurred with the current influenza A(H5N1) viruses circulating in the United States and globally.
Information for Local Health Departments
Frequently Asked Questions
- How are avian influenza viruses spread?
- What are the signs and symptoms of avian influenza viruses?
- Who is at risk for infection with avian influenza viruses?
- How do you protect yourself from avian influenza viruses spread from birds?
- Is treatment available for avian influenza viruses?
- What should I do if I become sick after having contact with birds or their environment?
- How are people tested for avian influenza viruses?
Information for Backyard Birds/Poultry or Bird Enthusiasts
Information for Clinicians
- Clinical Overview of Evaluating and Managing Patients Exposed to Birds Infected with Avian Influenza A Viruses of Public Health Concern
- Interim Guidance on the Use of Antiviral Medications for Treatment of Human Infections with Novel Influenza A Viruses Associated with Severe Human Disease
- Interim Guidance on Influenza Antiviral Chemoprophylaxis of Persons Exposed to Birds with Avian Influenza A Viruses Associated with Severe Human Disease or with the Potential to Cause Severe Human Disease
- Interim Guidance for Infection Control within Healthcare Settings when Caring for Confirmed or Probable Cases and Cases Under Investigation for Infection with Novel Influenza A Viruses Associated with Severe Disease
Fairs, Farms, and Occupational Workers
- Considerations and Information for Fair Exhibitors to Help Prevent Influenza
- Considerations and Information for Fair Organizers to Help Prevent Influenza
- Reducing Risk for People Working with or Exposed to Animals
- Self-Observation for Illness for Responders to Poultry Outbreaks of Avian Influenza
- Worker Protection and Use of Personal Protective Equipment (PPE)
Laboratory Specimen Information
- IDOH Specimen Collection and Transportation Instructions
- Electronic Lab Submission Through LimsNet
- Interim Guidance on Testing and Specimen Collection for Patients with Suspected Infection with Novel Influenza A Viruses with the Potential to Cause Severe Disease in Humans Testing Procedure for Laboratory Personnel
State and Federal Partner Resources
Contact Information
For healthcare providers requesting approval for specimen testing at IDOH Laboratory, please call the IDOH Infectious Disease Epidemiology and Prevention Division at 317-233-7125 to obtain approval from the Influenza Coordinator or the Vector-Borne and Zoonotic Disease Epidemiologist during normal business hours (Monday - Friday, 8:15am to 4:45pm).
- If calling after hours or on holidays, please contact the Epidemiologist On-Call (EOC) at 317-233-1325 for specimen testing approval.
For questions on specimen collection, transport, or shipment, please call the IDOH Laboratory Virology Division at 317-921-5500 during normal business hours (Monday - Friday, 8:15am to 4:45pm).
Page last reviewed/updated: February 2025