Avian Influenza (Flu)
Avian influenza (AI) viruses (sometimes referred to as bird flu) infect wild birds, poultry, and other mammals. AI viruses are divided into two groups based on the severity of the disease they produce in poultry: low pathogenicity avian influenza (LPAI) or highly pathogenic avian influenza (HPAI). While LPAI viruses typically cause milder illness and may circulate undetected, HPAI viruses are highly contagious and cause high mortality in poultry. While human illness to AI viruses are rare, both LPAI and HPAI viruses can cause human illness ranging from mild to severe.
What's Happening Now
HIGHLIGHTS: Current U.S. Bird Flu Situation in Humans
- Sporadic infections with highly pathogenic avian influenza A(H5N1) viruses in mammals have been reported in the United States, Canada, and other countries, but the risk to the general public remains low from these viruses.
- Influenza A(H5) is widespread in wild birds worldwide and is causing outbreaks in the U.S. poultry and dairy cattle with several recent human cases in U.S. dairy cattle workers.
- Only four human infections with low pathogenic avian influenza A(H7N2) viruses have ever been identified in the United States.
- No known human-to-human spread has occurred with the current influenza A(H5N1) viruses circulating in the United States and globally.
Frequently Asked Questions
- How are avian influenza viruses spread?
Infected birds shed AI viruses in their saliva, mucus, and feces. Human infections can occur when the AI virus is inhaled or gets into a person's eyes, nose, or mouth. This can happen when the virus is in the air (droplets or dust) and a person breathes the virus in, or when a person touches something that has the AI virus on it and then touches their mouth, eyes, or nose. People who have close contact with infected birds have the highest risk of infection.
Graphic: How Infected Backyard Poultry Spread Bird Flu to People (English) (Spanish) (Chinese) (K'iche) (Mamean) (Nahuatl)
- What are the signs and symptoms of avian influenza viruses?
AI viruses can cause mild to severe illness and are concerning because of their pandemic potential. Symptoms can include fever, chills, cough, sore throat, runny or stuffy nose, sneezing, shortness of breath, eye irritation or redness, fatigue, muscle or body aches, headaches, diarrhea, nausea or vomiting, and rash.
- Who is at risk for infection with avian influenza viruses?
Although AI viruses usually do not infect people, there have been some rare cases of human infection with these viruses. People who have job-related or recreational exposure to infected birds or animals, including cows, are at greater risk of contracting AI viruses. People with close or prolonged contact with infected birds or animals or their contaminated environments are at greater risk of infection.
- How do you protect yourself from avian influenza viruses spread from birds?
As a general precaution, whenever possible people should avoid direct contact with wild birds and other animals infected with or suspected to be infected with AI viruses and observe them only from a distance, if possible.
If you must handle infected or potentially infected birds or other animals, take extra precautions. AI virus infections in people happen most often after close, prolonged and unprotected (no gloves or other protective wear) contact with infected birds or other animals and their environments.
- Is treatment available for avian influenza viruses?
If you get sick after being exposed to sick or potentially infected birds, a healthcare provider may write you a prescription for an antiviral drug that is used for treatment of seasonal flu. These drugs can also treat avian influenza virus infection. It is important to start antiviral treatment as soon as possible and to follow the directions for taking all of the medication that is prescribed. Treatment should not be delayed while awaiting test results.
Treatment is not currently recommended for ill people whose only potential exposure is travel to an area (e.g. country, state/province, city, or county) with human cases of novel influenza A virus infection associated with severe human disease, or where these viruses are known to be circulating in animals.
- What should I do if I become sick after having contact with birds or their environment?
Human infections with avian influenza viruses are rare, and those with job-related or recreational exposures to infected bird or other animals are at higher risk of infection.
If you develop any of the signs or symptoms after an exposure, immediately call the health department of the state you are in at the time. Your health department wants to hear from you, even if it turns out to be a 'false alarm'. Your health department will give you further instructions and might ask you to get tested for avian influenza virus infection.
Until symptoms have resolved, or you have received further guidance from public health, stay home and limit contact with others as much as possible until the results of your test are known. Your health department might have additional instructions for you as well.
- How are people tested for avian influenza viruses?
To test for avian influenza virus, a healthcare provider will collect a sample from you by swabbing your nose and/or throat and possibly your eyes if you have eye redness or discomfort.
Information for Backyard Birds/Poultry or Bird Enthusiasts
Information for Clinicians
- Clinical Overview of Evaluating and Managing Patients Exposed to Birds Infected with Avian Influenza A Viruses of Public Health Concern
- Interim Guidance on the Use of Antiviral Medications for Treatment of Human Infections with Novel Influenza A Viruses Associated with Severe Human Disease
- Interim Guidance on Influenza Antiviral Chemoprophylaxis of Persons Exposed to Birds with Avian Influenza A Viruses Associated with Severe Human Disease or with the Potential to Cause Severe Human Disease
- Interim Guidance for Infection Control within Healthcare Settings when Caring for Confirmed or Probable Cases and Cases Under Investigation for Infection with Novel Influenza A Viruses Associated with Severe Disease
Fairs, Farms, and Occupational Workers
- Considerations and Information for Fair Exhibitors to Help Prevent Influenza
- Considerations and Information for Fair Organizers to Help Prevent Influenza
- Reducing Risk for People Working with or Exposed to Animals
- Self-Observation for Illness for Responders to Poultry Outbreaks of Avian Influenza
- Worker Protection and Use of Personal Protective Equipment (PPE)
Laboratory Specimen Information
- IDOH Specimen Collection and Transportation Instructions
- Electronic Lab Submission Through LimsNet
- Interim Guidance on Testing and Specimen Collection for Patients with Suspected Infection with Novel Influenza A Viruses with the Potential to Cause Severe Disease in Humans Testing Procedure for Laboratory Personnel
State and Federal Partner Resources
Contact Information
For healthcare providers requesting approval for specimen testing at IDOH Laboratory, please call the IDOH Infectious Disease Epidemiology and Prevention Division at 317-233-7125 to obtain approval from the Influenza Coordinator or the Vector-Borne and Zoonotic Disease Epidemiologist during normal business hours (Monday - Friday, 8:15am to 4:45pm).
- If calling after hours or on holidays, please contact the Epidemiologist On-Call (EOC) at 317-233-1325 for specimen testing approval.
For questions on specimen collection, transport, or shipment, please call the IDOH Laboratory Virology Division at 317-921-5500 during normal business hours (Monday - Friday, 8:15am to 4:45pm).
Page last reviewed/updated: October 2024